Applied Photophysics is a worldleading manufacturer and supplier of precision spectrometers for the study of circular dichroism, stoppedflow kinetics and laser flash photolysis. The company supplies the lifesciences community in both academic and commercial spheres with instruments that are used to study the structural, thermodynamic and kinetic properties in solution of a wide range of samples. The current main product range comprises the Chirascan circular dichroism spectrometer, the SX20 stoppedflow spectrometer and the LKS.60 laser flash photolysis spectrometer. Chirascan The next generation in circular dichroism Applied Photophysics Chirascan is the most advanced circular dichroism spectrometer available today. It is particularly valuable in elucidating the higher structures of biomacromolecules in solution, for example the secondary structures of proteins, DNA and RNA, and how these structures change when stressed by temperature, pH or other means such as drug binding. Chirascan needs only very small quantities of sample to rapidly and conveniently generate accurate and precise circular dichroism spectra that inform the researcher about the secondary and often the tertiary structures of the system under study. Such structural information is used in establishing if a protein is correctly folded or if proteins from different processes have identical conformations, how higher structures of proteins or DNA change on binding to a drug, whether or not a particular biotherapeutic formulated in one buffer is more stable than in another and many more applications in a similar vein.

Address: Applied Photophysics Ltd 203205 Kingston Road Leatherhead Surrey KT22 7PB United Kingdom
Telephone: 0044 01372 386537
Fax: 0044 01372 386 477
Website: http://www.photophysics.com/